Is this project an undergraduate, graduate, or faculty project?
Undergraduate
Project Type
group
Campus
Daytona Beach
Authors' Class Standing
Legacy Wilson, Sophomore
Lead Presenter's Name
Legacy Wilson
Lead Presenter's College
DB College of Arts and Sciences
Faculty Mentor Name
Dr. Jenny Vu
Abstract
Title: Chemical Profiling of Star Anise (Illicium verum) via GC–MS: Identifying Compounds with Pharmaceutical Potential Abstract: Star anise (Illicium verum) has been used for both medicinal and culinary applications due to its diverse bioactive compounds. It is a primary natural source of shikimic acid (𝐶7𝐻10𝑂5), a key precursor in the synthesis of the antiviral drug oseltamivir (Tamiflu), used to treat influenza. Additionally, star anise has been used to treat respiratory and digestive conditions and is widely used for flavoring due to its licorice-like aroma, mainly from trans-anethole (𝐶10𝐻12𝑂) , its major component. Previous studies have also demonstrated mild central nervous system effects, including reduced activity and analgesic properties in mice. Given its pharmacological potential, this study aimed to chemically characterize the essential oil components of star anise. Steam distillation was used to isolate the compounds by co-distillation with water, forming a hydrosol. The hydrosol was extracted using methyl tert-butyl ether (MTBE) in a separatory funnel. The organic layer was washed with brine, dried with sodium sulfate, and transferred to a scintillation vial. Gas chromatography–mass spectrometry (GC-MS) was used to separate and identify the compounds present. The analysis revealed trans-anethole as the major compound (148.2 g/mol), followed by p-anisaldehyde, estragole, limonene, and linalool. Trans-anethole, estragole, and p-anisaldehyde are aromatic, limonene is a hydrocarbon, and linalool is a non-aromatic alcohol. These functional groups influence their relative abundance and extraction efficiency. A total of 0.071 g of essential oil was obtained. Overall, this study highlights the chemical diversity of star anise and its relevance as a source of pharmaceutically significant compounds.The analysis revealed trans-anethole as the major compound (148.2 g/mol), followed by p-anisaldehyde, estragole, limonene, and linalool. Trans-anethole, estragole, and p-anisaldehyde are aromatic, limonene is a hydrocarbon, and linalool is a non-aromatic a Given its pharmacological potential, this study aimed to chemically characterize the essential oil components of star anise. Steam distillation was used to isolate volatile compounds by co-distillation with water, forming a hydrosol. The hydrosol was extracted using methyl tert-butyl ether (MTBE) in a separatory funnel. The organic layer was washed with brine, dried with sodium sulfate, and transferred to a scintillation vial. Gas chromatography–mass spectrometry (GC-MS) was used to separate and identify the compounds present.Given its pharmacological potential, this study aimed to chemically characterize the essential oil components of star anise. Steam distillation was used to isolate volatile compounds by co-distillation with water, forming a hydrosol. The hydrosol was extracted using methyl tert-butyl ether (MTBE) in a separatory funnel. The organic layer was washed with brine, dried with sodium sulfate, and transferred to a scintillation vial. Gas chromatography–mass spectrometry (GC-MS) was used to separate and identify the compounds present. The analysis revealed trans-anethole as the major compound (148.2 g/mol), followed by p-anisaldehyde, estragole, limonene, and linalool. Trans-anethole, estragole, and p-anisaldehyde are aromatic, limonene is a hydrocarbon, and linalool is a non-aromatic alcohol. These functional groups influence their relative abundance and extraction efficiency. A total of 0.071 g of essential oil was obtained. Overall, this study highlights the chemical diversity of star anise and its relevance as a source of pharmaceutically significant compounds.
Did this research project receive funding support (Spark, SURF, Research Abroad, Student Internal Grants, Collaborative, Climbing, or Ignite Grants) from the Office of Undergraduate Research?
No
Included in
Analytical Chemistry Commons, Medicinal-Pharmaceutical Chemistry Commons, Organic Chemistry Commons
Chemical Profiling of Star Anise (Illicium verum) via GC–MS: Identifying Compounds with Pharmaceutical Potential
Title: Chemical Profiling of Star Anise (Illicium verum) via GC–MS: Identifying Compounds with Pharmaceutical Potential Abstract: Star anise (Illicium verum) has been used for both medicinal and culinary applications due to its diverse bioactive compounds. It is a primary natural source of shikimic acid (𝐶7𝐻10𝑂5), a key precursor in the synthesis of the antiviral drug oseltamivir (Tamiflu), used to treat influenza. Additionally, star anise has been used to treat respiratory and digestive conditions and is widely used for flavoring due to its licorice-like aroma, mainly from trans-anethole (𝐶10𝐻12𝑂) , its major component. Previous studies have also demonstrated mild central nervous system effects, including reduced activity and analgesic properties in mice. Given its pharmacological potential, this study aimed to chemically characterize the essential oil components of star anise. Steam distillation was used to isolate the compounds by co-distillation with water, forming a hydrosol. The hydrosol was extracted using methyl tert-butyl ether (MTBE) in a separatory funnel. The organic layer was washed with brine, dried with sodium sulfate, and transferred to a scintillation vial. Gas chromatography–mass spectrometry (GC-MS) was used to separate and identify the compounds present. The analysis revealed trans-anethole as the major compound (148.2 g/mol), followed by p-anisaldehyde, estragole, limonene, and linalool. Trans-anethole, estragole, and p-anisaldehyde are aromatic, limonene is a hydrocarbon, and linalool is a non-aromatic alcohol. These functional groups influence their relative abundance and extraction efficiency. A total of 0.071 g of essential oil was obtained. Overall, this study highlights the chemical diversity of star anise and its relevance as a source of pharmaceutically significant compounds.The analysis revealed trans-anethole as the major compound (148.2 g/mol), followed by p-anisaldehyde, estragole, limonene, and linalool. Trans-anethole, estragole, and p-anisaldehyde are aromatic, limonene is a hydrocarbon, and linalool is a non-aromatic a Given its pharmacological potential, this study aimed to chemically characterize the essential oil components of star anise. Steam distillation was used to isolate volatile compounds by co-distillation with water, forming a hydrosol. The hydrosol was extracted using methyl tert-butyl ether (MTBE) in a separatory funnel. The organic layer was washed with brine, dried with sodium sulfate, and transferred to a scintillation vial. Gas chromatography–mass spectrometry (GC-MS) was used to separate and identify the compounds present.Given its pharmacological potential, this study aimed to chemically characterize the essential oil components of star anise. Steam distillation was used to isolate volatile compounds by co-distillation with water, forming a hydrosol. The hydrosol was extracted using methyl tert-butyl ether (MTBE) in a separatory funnel. The organic layer was washed with brine, dried with sodium sulfate, and transferred to a scintillation vial. Gas chromatography–mass spectrometry (GC-MS) was used to separate and identify the compounds present. The analysis revealed trans-anethole as the major compound (148.2 g/mol), followed by p-anisaldehyde, estragole, limonene, and linalool. Trans-anethole, estragole, and p-anisaldehyde are aromatic, limonene is a hydrocarbon, and linalool is a non-aromatic alcohol. These functional groups influence their relative abundance and extraction efficiency. A total of 0.071 g of essential oil was obtained. Overall, this study highlights the chemical diversity of star anise and its relevance as a source of pharmaceutically significant compounds.