One way to explore special nuclear material properties is to study how a metal surface breaks up into ejected particulates when an extreme explosive shock is applied to the metal. To understand the physical processes that govern this release, it is necessary to measure the size distribution of the cloud of ejecta particles in situ. The fastest high-resolution camera in the world cannot capture the information we need. Working with National Security Technologies, LLC Signals Processing, and Applied Mathematics Research Group, our team used simulated data and exiting analysis codes to inform our industry partner how best to set up this Mie Scattering-based particle sizing diagnostic.