Author

Arka Das

Date of Award

7-12-2021

Document Type

Dissertation - Open Access

Degree Name

Doctor of Philosophy in Mechanical Engineering

Department

Mechanical Engineering

Committee Chair

Eduardo Divo, Ph.D.

First Committee Member

Dr. Fardin Khalili

Second Committee Member

Dr. Birce Dikici

Third Committee Member

Dr. Alain Kassab

Fourth Committee Member

Dr. William DeCampli

Abstract

Single ventricle (SV) anomalies account for one-fourth of all cases of congenital Heart disease. The conventional second and third stage i.e. Comprehensive stage II and Fontan procedure of the existing three-staged surgical approach serving as a palliative treatment for this anomaly, entails multiple complications and achieves a survival rate of 50%. Hence, to reduce the morbidity and mortality rate associated with the second and third stages of the existing palliative procedure, the novel alternative techniques called “Hybrid Comprehensive Stage II” (HCSII), and a “Self-powered Fontan circulation” have been proposed. The goal of this research is to conduct in-vitro investigations to validate computational and clinical findings on these proposed novel surgical techniques. The research involves the development of a benchtop study of HCSII and self-powered Fontan circulation.

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