Location
Howard Johnson Plaza-Hotel, Columbia/ Enterprise Rooms
Start Date
24-4-1990 2:00 PM
End Date
24-4-1990 5:00 PM
Description
The basilar papilla is the hearing portion of the bird f s inner ear and serves as a model for human inner ear development. We used neuron-specific enolase (NSE) as a marker for the chick T s auditory nerve (statoacoustic ganglion) development. The chick hatches after an incubation period of 3 weeks. At stage 38 (12th embryonic day), the earliest stage examined in the present experiments, we observed faint NSE staining (immunoreactivity) in neurons of the statoacoustic ganglion. By stage 39- «13th embryonic day), stronger NSE immunoreacti vi ty appeared in most neuronal cell bodies (perikarya). By stage 46 (21st day [hatching]), neurons stained strongly for NSE. Thus, NSE levels (immunoreactivities) increase during development and correspond to neuronal differentiation.
Paper Session I-B - Developmental Appearance of Neuron-Specific Enolase in the Embryonic Chick's Basilar Papilla
Howard Johnson Plaza-Hotel, Columbia/ Enterprise Rooms
The basilar papilla is the hearing portion of the bird f s inner ear and serves as a model for human inner ear development. We used neuron-specific enolase (NSE) as a marker for the chick T s auditory nerve (statoacoustic ganglion) development. The chick hatches after an incubation period of 3 weeks. At stage 38 (12th embryonic day), the earliest stage examined in the present experiments, we observed faint NSE staining (immunoreactivity) in neurons of the statoacoustic ganglion. By stage 39- «13th embryonic day), stronger NSE immunoreacti vi ty appeared in most neuronal cell bodies (perikarya). By stage 46 (21st day [hatching]), neurons stained strongly for NSE. Thus, NSE levels (immunoreactivities) increase during development and correspond to neuronal differentiation.
Comments
Science Payloads
Session Chairman: Joe Alexander, NASA Assistant Associate Administrator for Space Science and Applications, NASA Headquarters
Session Organizer: Lee O’Fallon, NASA, Kennedy Space Center