Is this project an undergraduate, graduate, or faculty project?
Undergraduate
Project Type
group
Campus
Daytona Beach
Authors' Class Standing
Jaden McBride, Junior Ashley Lunt, Freshman
Lead Presenter's Name
Jaden McBride
Lead Presenter's College
DB College of Arts and Sciences
Faculty Mentor Name
Alba Chavez
Abstract
Oral biofilms, comprising diverse microbial communities residing on oral surfaces, play a pivotal role in oral health and disease. Understanding the antimicrobial profile of these biofilms is crucial for developing effective strategies to combat oral infections and maintain oral hygiene. Here we report the antimicrobial profile of Micrococcus lutens, a bacteria found as part of the mouth microflora. We tested using a comprehensive microtiter inhibition assay the antibacterial profile using a total of 12 antibacterial agents. Prelimary results indicate that bacteria are susceptible to four agents in a free-living form; however, biofilms (or bacterial communities) are resistant to all of the agents tested. Future studies include the analysis of synergistic interactions between conventional antibiotics and adjunctive therapies provide enhanced efficacy in biofilm eradication.
Did this research project receive funding support (Spark, SURF, Research Abroad, Student Internal Grants, Collaborative, Climbing, or Ignite Grants) from the Office of Undergraduate Research?
Yes, Spark Grant
Antimicrobial Profile of Oral Biofilms: Insights and Implications
Oral biofilms, comprising diverse microbial communities residing on oral surfaces, play a pivotal role in oral health and disease. Understanding the antimicrobial profile of these biofilms is crucial for developing effective strategies to combat oral infections and maintain oral hygiene. Here we report the antimicrobial profile of Micrococcus lutens, a bacteria found as part of the mouth microflora. We tested using a comprehensive microtiter inhibition assay the antibacterial profile using a total of 12 antibacterial agents. Prelimary results indicate that bacteria are susceptible to four agents in a free-living form; however, biofilms (or bacterial communities) are resistant to all of the agents tested. Future studies include the analysis of synergistic interactions between conventional antibiotics and adjunctive therapies provide enhanced efficacy in biofilm eradication.