Author Information

Jaden McBride
Ashley Lunt

Is this project an undergraduate, graduate, or faculty project?

Undergraduate

Project Type

group

Campus

Daytona Beach

Authors' Class Standing

Jaden McBride, Junior Ashley Lunt, Freshman

Lead Presenter's Name

Jaden McBride

Lead Presenter's College

DB College of Arts and Sciences

Faculty Mentor Name

Alba Chavez

Abstract

Oral biofilms, comprising diverse microbial communities residing on oral surfaces, play a pivotal role in oral health and disease. Understanding the antimicrobial profile of these biofilms is crucial for developing effective strategies to combat oral infections and maintain oral hygiene. Here we report the antimicrobial profile of Micrococcus lutens, a bacteria found as part of the mouth microflora. We tested using a comprehensive microtiter inhibition assay the antibacterial profile using a total of 12 antibacterial agents. Prelimary results indicate that bacteria are susceptible to four agents in a free-living form; however, biofilms (or bacterial communities) are resistant to all of the agents tested. Future studies include the analysis of synergistic interactions between conventional antibiotics and adjunctive therapies provide enhanced efficacy in biofilm eradication.

Did this research project receive funding support (Spark, SURF, Research Abroad, Student Internal Grants, Collaborative, Climbing, or Ignite Grants) from the Office of Undergraduate Research?

Yes, Spark Grant

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Antimicrobial Profile of Oral Biofilms: Insights and Implications

Oral biofilms, comprising diverse microbial communities residing on oral surfaces, play a pivotal role in oral health and disease. Understanding the antimicrobial profile of these biofilms is crucial for developing effective strategies to combat oral infections and maintain oral hygiene. Here we report the antimicrobial profile of Micrococcus lutens, a bacteria found as part of the mouth microflora. We tested using a comprehensive microtiter inhibition assay the antibacterial profile using a total of 12 antibacterial agents. Prelimary results indicate that bacteria are susceptible to four agents in a free-living form; however, biofilms (or bacterial communities) are resistant to all of the agents tested. Future studies include the analysis of synergistic interactions between conventional antibiotics and adjunctive therapies provide enhanced efficacy in biofilm eradication.

 

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