Is this project an undergraduate, graduate, or faculty project?

Graduate

group

What campus are you from?

Daytona Beach

Authors' Class Standing

Janelle Hicks, Graduate Student

Lead Presenter's Name

Janelle Hicks

Faculty Mentor Name

Hugo Castillo

Abstract

Microbial communities within the human gut play an important role in our overall health and wellbeing. Understanding how microgravity affects these microbial communities provides greater insight into the health of astronauts on board the ISS and what may occur during Deep Space explorations. Previous experiments have measured differential gene expression of single culture bacteria exposed to simulated microgravity, allowing us to map which genes are selected for or against in that environment. Using fecal pellets from mice exposed to simulated microgravity and space radiation, we are constructing and sequencing RNA and DNA libraries to study the metatranscriptome and changes in gut microbiota. These comparisons will allow us to gain a better understanding of how microbial communities are affected by space environments and what that may entail for the gut health of astronauts.

Did this research project receive funding support from the Office of Undergraduate Research.

No

Share

COinS
 

Differential Gene Expression of Mice Pellet Microbial Communities exposed to Simulated Microgravity

Microbial communities within the human gut play an important role in our overall health and wellbeing. Understanding how microgravity affects these microbial communities provides greater insight into the health of astronauts on board the ISS and what may occur during Deep Space explorations. Previous experiments have measured differential gene expression of single culture bacteria exposed to simulated microgravity, allowing us to map which genes are selected for or against in that environment. Using fecal pellets from mice exposed to simulated microgravity and space radiation, we are constructing and sequencing RNA and DNA libraries to study the metatranscriptome and changes in gut microbiota. These comparisons will allow us to gain a better understanding of how microbial communities are affected by space environments and what that may entail for the gut health of astronauts.

 

To view the content in your browser, please download Adobe Reader or, alternately,
you may Download the file to your hard drive.

NOTE: The latest versions of Adobe Reader do not support viewing PDF files within Firefox on Mac OS and if you are using a modern (Intel) Mac, there is no official plugin for viewing PDF files within the browser window.