Is this project an undergraduate, graduate, or faculty project?
Undergraduate
individual
What campus are you from?
Daytona Beach
Authors' Class Standing
Kaitlyn Nielsen, Senior
Lead Presenter's Name
Kaitlyn Nielsen
Faculty Mentor Name
Foram Madiyar
Abstract
Nanofibers provide revolutionary means for drug delivery. pH-sensitive nanofibers will be fabricated, using electro spraying or electrospinning, and will be prepared using trimethyl-chitosan (TMC), poly(ethylene glycol)dimethacrylate (PEGDMA) and methacrylic acid (MAA) by free radical suspension polymerization, for the oral delivery of interferon-β (INF-β) as a method drug dosage form for the treatment of multiple sclerosis. The nanofibers will be subsequently compressed into a suitable dosage form. The prepared copolymeric nanofiber system will be characterized for its morphological and mucoadhesive properties. This research will support current scientific efforts to identify a “best-practice” method for preventing the regression of multiple sclerosis.
Did this research project receive funding support from the Office of Undergraduate Research.
Yes, Ignite Grant
A novel pH-sensitive interferon-β oral delivery system using electrospray/spin for application in multiple sclerosis - A Chemical Investigation
Nanofibers provide revolutionary means for drug delivery. pH-sensitive nanofibers will be fabricated, using electro spraying or electrospinning, and will be prepared using trimethyl-chitosan (TMC), poly(ethylene glycol)dimethacrylate (PEGDMA) and methacrylic acid (MAA) by free radical suspension polymerization, for the oral delivery of interferon-β (INF-β) as a method drug dosage form for the treatment of multiple sclerosis. The nanofibers will be subsequently compressed into a suitable dosage form. The prepared copolymeric nanofiber system will be characterized for its morphological and mucoadhesive properties. This research will support current scientific efforts to identify a “best-practice” method for preventing the regression of multiple sclerosis.